Clinical reports

Marchese A, Debbia EA, Schito GC. Evaluation Of Spontaneous Microbial Contamination Of Ocular Medications After First Opening. Giornale Italiano di Microbiologia Medica Odontoiatrica e Clinica Vol. IV, 2, 2000, p. 93-102, Copyright 2000
Marchese A, M.Bozzolasco M, Gualco L,Schito GC, Debbia EA Evaluation of Spontaneous Contamination of Ocular Medications, Institute of Microbiology ‘C.A. Romanzi’, University of Genoa School of Medicine, Genoa, Italy Chemotherapy 2001;47:304–308

Papers on dry eye

Papers on dry eye

1. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. Apr 2007;5(2):75-92. [PubMed]

2. McDonnell PJ, Doyle JJ, Stern L, Behrens A, and the Dysfunctional Tear Syndrome Group. A modified Delphi technique to obtain consensus on the treatment of dysfunctional tear syndrome. Presented at: Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO); April 25-29, 2004: Fort Lauderdale, FL. [Abstract]

3. Brodwall J, Alme G, Gedde-Dahl S, Smith J, Lilliedahl NP, Kunz PA, Sunderraj P. A comparative study of polyacrylic acid (Viscotears) liquid gel versus polyvinylalcohol in the treatment of dry eyes. Acta Ophthalmol Scand. 1997 Aug;75(4):457-61. [PubMed]

4. Bron AJ, Mangat H, Quinlan M, Foley-Nolan A, Eustace P, Fsadni M, Sunder Raj P. Polyacrylic acid gel in patients with dry eyes: a randomised comparison with polyvinyl alcohol. Eur J Ophthalmol. 1998 Apr-Jun;8(2):81-9. [PubMed]

5. Aragona P, Papa V, Micali A, Santocono M. Long term treatment with sodium hyaluronate-containing artificial tears reduces ocular surface damage in patients with dry eye. BrJ Ophthalmol 2002;86:181-184 [PubMed]

6. Aragona P, Di Stefano G,Ferreri F,Spinella R, Stilo. A Sodium hyaluronate eye drops of different osmolarity for the treatment of dry eye in Sjögren’s syndrome patients. Br J Ophthalmol 2002;86:879–884 [PubMed]

7. Gomes JAP, Amankwah R, Powell-Richards A, Dua HS. Sodium hyaluronate (hyaluronic acid) promotes migration of human corneal epithelial cells in vitro. Br J Ophthalmol 2004;88:821–825 [PubMed]

8. Tamasco PP, Leri A, Nardi M Treatment of eye dryness with hyaluronic acid eyedrops, Symposium on the Lacrimal System, Bruxelles, May 23-24 1992.


Papers on blepharitis

New paper advises on eye lid margin hygiene.

Dr. Khaireddin, Dr Hüber, Eyelid hygiene for contact lens wearers with blepharitis. Ophthalmologe 2013 · 110:146–153 [PubMed]



Comparison of use of baby shampoo with phospholipid-liposomal solution for lid margin hygiene.

The paper concludes that although both therapies improved the symptoms of dry eye due to blepharitis in symptomatic contact lens wearers, patients using phospholipid-liposomal solution for lid margin hygiene demonstrated a significantly greater clinical benefit from the therapy. 

Thus, clinical practice recommending just baby shampoo for lid margin hygiene should be re-considered, as phospholipid-liposomal solution for lid margin hygiene appears to yield greater and faster clinical benefits for symptomatic contact lens wearers suffering from dry eye symptoms

Dry eye monographs

Clinitas (Sodium Hyaluronate 0.4%): Management Review And Evaluation Document

Clinitas: Technical Information (Re-sealing)

Clinitas Hydrate Technical Product Summary And Clinical Data

Clinitas Carbomer Gel: Technical data sheet and summary of product characteristics

Clinitas Carbomer Gel: Technical Product Summary And Clinical Data

Review Of The Eye Preparation Clinitas Gel (Carbomer 0.2%) In Respect Of Efficacy In Dry Eye And To Include Safety And Economic Evaluation

Clinitas Ultra 3 Technical Product Summary And Clinical Data